Diastereoselective synthesis of substituted diaziridines from simple ketones and aldehydes.
نویسندگان
چکیده
Diastereopure substituted diaziridines from simple ketones, aldehydes and amines are here reported. These important chemical scaffolds are obtained in the presence of a weak inorganic base and hydroxylamine O-sulfonic acid (HOSA). This method introduces three stereocenters in one step to provide a wide variety of substituted diaziridines with high yields and diastereoselectivities.
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ورودعنوان ژورنال:
- Chemical communications
دوره 51 70 شماره
صفحات -
تاریخ انتشار 2015